HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzonitrile, 3-(bromomethyl)- → 3-[[[5-[3-[4-(Methylsulfinyl)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazol-2-yl]thio]methyl]benzonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzonitrile, 3-(bromomethyl)- | HCID 97249 | — |
| Edukt | HCID 178504596 | HCID 178504596 | — |
| Produkt | 3-[[[5-[3-[4-(Methylsulfinyl)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazol-2-yl]thio]methyl]benzonitrile | HCID 68664277 | 76% |
Reaktionsschritte
In the same manner as in Example 7 and using 5-[3-[4-(methylsulfinyl)phenyl]-1-benzofuran-5-yl]-1,3,4-oxadiazole-2-thiol instead of 5-(1H-indazol-5-yl)-1,3,4-oxadiazole-2-thiol and 3-(bromomethyl)benzonitrile instead of 3-(trifluoromethyl)benzyl chloride, the title compound (yield 76%) was obtained as colorless crystals.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08492378B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-bea6f6dadf0044a99d3fab003b50561d |
| Quellennotiz | uspto-grants-2013_07 |