2-Methyl-5-nitro-1H-indole → 5-Amino-2-methylindole

Beteiligte Stoffe

Reaktionsschritte

A solution of 2-methyl-5-nitroindole (1 g, 5.7 mmol) in ethanol (25 ml) and THF (25 ml) containg 10% palladium on charcoal (128 mg) was hydrogenated until uptake of hydrogen ceased. The mixture was filtered and the filtrate was evaporated to give 5-amino-2-methylindole (830 mg, quant.).

Herkunft & Nachweise