Sodium Hydroxide → HCID 58508470, Verbindung

HRID 454773Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 454773
[OH-].[Na+:2].[OH:3][C:4]1[CH:5]=[C:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[C:12]([NH:19][C:20]([C:22]3[CH:23]=[N:24][CH:25]=[C:26]([C:28]4[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=4)[CH:27]=3)=[O:21])[CH:11]=2)[CH:7]=[CH:8][CH:9]=1>C(O)C>[OH:3][C:4]1[CH:5]=[C:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([O-:16])=[O:15])=[C:12]([NH:19][C:20]([C:22]3[CH:23]=[N:24][CH:25]=[C:26]([C:28]4[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=4)[CH:27]=3)=[O:21])[CH:11]=2)[CH:7]=[CH:8][CH:9]=1.[Na+:2]

Komponenten

4

Edukt 2

HCID 14798Sodium HydroxideHCID 58508471HCID 58508471, Verbindung

Produkt 1

HCID 58508470HCID 58508470, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Ethanol (4.0 mL) and a 1 mol/L aqueous solution of sodium hydroxide (0.17 mL) were sequentially added to the obtained 4-(3-hydroxyphenyl)-2-(5-phenylpyridine-3-carboxamido)benzoic acid (70 mg), followed by stirring at room temperature for 1 hour. The solvent was evaporated under reduced pressure, and ethanol and water were added to the obtained residue. The solid substance was collected by filtration to obtain 26 mg of sodium 4-(3-hydroxyphenyl)-2-(5-phenylpyridine-3-carboxamido)benzoate as a white solid.

Aufarbeitung

  1. customThe solvent was evaporated under reduced pressure, and ethanol and water
  2. additionwere added to the obtained residue
  3. filtrationThe solid substance was collected by filtration

Quellen und Nachweise

ORD-Eintrag
ord-32d6ad06ef954c4fa475b9c67cc8f555
Quelldatensatz
uspto-grants-2013_07
Patentnummer
US08492582B2

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