HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Amino-4-methoxybenzoic acid → (3-Amino-4-methoxy-phenyl)-(cis-2,3,4,4a,9,9a-hexahydro-indeno[2,1-b]pyridin-1-yl)-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Amino-4-methoxybenzoic acid | HCID 17823 | — |
| Edukt | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Edukt | cis-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine | HCID 58123900 | — |
| Produkt | (3-Amino-4-methoxy-phenyl)-(cis-2,3,4,4a,9,9a-hexahydro-indeno[2,1-b]pyridin-1-yl)-methanone | HCID 67224459 | 77% |
Reaktionsschritte
The title compound is prepared from 3-amino-4-methoxy-benzoic acid and cis-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine following a procedure analogous to that described in Example 1 [2-(7-aza-1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexa-fluorophosphate is used]. Yield: 77% of theory; LC (method 4): tR=1.75 min; Mass spectrum (ESI+): m/z=323 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08497281B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-7244fe583df542cab34ca7a92998a4b3 |
| Quellennotiz | uspto-grants-2013_07 |