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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 456023Erstellt: 25. Oktober 2026

4'-Chloro-4-biphenylol → 2-[(4-{[(4'-Chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester

https://huagongshe.com/reaction/456023

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4'-Chloro-4-biphenylolHCID 91589—
EduktHCID 58451403HCID 58451403—
Produkt2-[(4-{[(4'-Chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl esterHCID 6739224917,1%

Reaktionsschritte

By an operation similar to that in Example 2-1 and using 2-{[4-(chloroacetyl)-1,3-thiazol-2-yl]thio}-2-methylpropionic acid tert-butyl ester (561 mg) obtained in Example 1 and 4′-chlorobiphenyl-4-ol (307 mg), 2-[(4-{[(4′-chlorobiphenyl-4-yl)oxy]acetyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester (129 mg) was obtained. Furthermore, by operations similar to those in Example 2-2 and 2-3, the title compound (36 mg) was obtained.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08497382B2
Quelldatensatzuspto-grants-2013_07
ORD IDord-69fa158aac1f4098a89e987794ae1037
Quellennotizuspto-grants-2013_07