N,N'-Dicyclohexylurea → N'-(6-Chloropyridazin-3-yl)-2-(quinolin-6-yl)acetohydrazide

Beteiligte Stoffe

Reaktionsschritte

To a suspension of 3-chloro-6-hydrazinylpyridazine (3 g, 20.75 mmol) and 2-(quinolin-6-yl)acetic acid (4.27 g, 22.83 mmol) in 200 ml DCM was added DCC (5.14 g, 24.90 mmol). The solution was stirred at room temperature for overweekend. The title compound as a white solid containing dicyclohexyl urea was filtered and used in the next step without further purification (8 g, 100%). LCMS (method A): [MH]+=314.1, tR=2.85 min.

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