Hydrochloric Acid → Methyl 2-(5-bromo-2-methoxyphenyl)acetate

HRID 456195

Reaktionsgleichung

Reaktionsgleichung von HRID 456195
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:12][CH3:13])=[C:6]([CH2:8][C:9]([OH:11])=[O:10])[CH:7]=1.Cl.[CH3:15]O>>[CH3:15][O:10][C:9](=[O:11])[CH2:8][C:6]1[CH:7]=[C:2]([Br:1])[CH:3]=[CH:4][C:5]=1[O:12][CH3:13]

Komponenten

4

Edukt 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 5553065-Bromo-2-methoxyphenylacetic acid

Produkt 1

HCID 21999895Methyl 2-(5-bromo-2-methoxyphenyl)acetate

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

To 5-bromo-2-methoxyphenylacetic acid (0.900 g, 3.7 mmol) in MeOH (20 mL) was added hydrogen chloride (4N in 1,4-dioxane; 4 mL), and the reaction was stirred at 80° C. for 6 hours. The mixture was then concentrated to dryness to give the title compound.

Aufarbeitung

  1. concentrationThe mixture was then concentrated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-6468b8e4aa80453a951593f3be6a0500
Quelldatensatz
uspto-grants-2013_07
Patentnummer
US08497381B2

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