1-Bromo-2-(bromomethyl)-4-fluorobenzene → (4S,5R)-3-(2-Bromo-5-fluoro-benzyl)-4-methyl-5-phenyl-oxazolidin-2-one
Reaktionsgleichung
[Br:1][C:2]1[CH:9]=[CH:8][C:7]([F:10])=[CH:6][C:3]=1[CH2:4]Br.[CH3:11][C@H:12]1[C@@H:16]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[O:15][C:14](=[O:23])[NH:13]1>>[Br:1][C:2]1[CH:9]=[CH:8][C:7]([F:10])=[CH:6][C:3]=1[CH2:4][N:13]1[C@@H:12]([CH3:11])[C@@H:16]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[O:15][C:14]1=[O:23]Komponenten
3
Versuchsvorschrift
Prepared according to the procedure described in Example 1, Step 3, using the following starting materials: 2-bromo-5-fluorobenzyl bromide and (4S,5R)-(−)-4-methyl-5-phenyl-2-oxazolidinone.
Aufarbeitung
- customPrepared
Quellen und Nachweise
- ORD-Eintrag
- ord-46110db2ba994ee8b6cc76f1887482f5