2-Phenyl-1-propanol → N-[4-(2-Phenylpropoxy)benzoyl]glycine
Reaktionsgleichung
C([O:5][C:6](=[O:18])[CH2:7][NH:8][C:9](=[O:17])[C:10]1[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=1)(C)(C)C.[C:19]1([CH:25]([CH3:28])[CH2:26]O)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[C:19]1([CH:25]([CH3:28])[CH2:26][O:16][C:13]2[CH:12]=[CH:11][C:10]([C:9]([NH:8][CH2:7][C:6]([OH:5])=[O:18])=[O:17])=[CH:15][CH:14]=2)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1Komponenten
3
Versuchsvorschrift
The same reaction as in Example 1 (1b) was conducted using N-(4-hydroxybenzoyl)glycine tert-butyl ester (247 mg, 0.983 mmol) prepared in Example 1 (1a) and 2-phenylpropan-1-ol (185 μL, 1.32 mmol) to give 221 mg of the title compound (white powder, yield: 72%).
Quellen und Nachweise
- ORD-Eintrag
- ord-732fcd1126af40698b572ccf3ab0506e
- Quelldatensatz
- uspto-grants-2013_07