HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(2-Fluorophenyl)ethan-1-ol → N-{4-[2-(2-Fluorophenyl)ethoxy]benzoyl}glycine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(2-Fluorophenyl)ethan-1-ol | HCID 2733296 | — |
| Edukt | N-(4-Hydroxybenzoyl)glycine tert-butyl ester | HCID 10682169 | — |
| Produkt | N-{4-[2-(2-Fluorophenyl)ethoxy]benzoyl}glycine | HCID 66811873 | 73,4% |
Reaktionsschritte
The same reaction as in Example 1 (1b) was conducted using N-(4-hydroxybenzoyl)glycine tert-butyl ester (231 mg, 0.919 mmol) prepared in Example 1 (1a) and 2-(2-fluorophenyl)ethanol (137 μL, 1.02 mmol) to give 214 mg of the title compound (white powder, yield: 73%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08497397B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-7e1957fc67d34f99b2c613230d83fceb |
| Quellennotiz | uspto-grants-2013_07 |