HCID 20760150, Verbindung → HCID 67378457, Verbindung
Reaktionsgleichung
[OH:1][C@H:2]([CH2:16][OH:17])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH2:11][CH2:12][CH2:13][CH2:14][NH2:15].C(NCCCCC1C=CC=CC=1OC[C@@H](O)CO)(OCC1C=CC=CC=1)=O>>[OH:1][C@@H:2]([CH2:16][OH:17])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH2:11][CH2:12][CH2:13][CH2:14][NH2:15]Komponenten
3
Versuchsvorschrift
Compound 73 was prepared in a similar fashion to the synthesis of compound 70 starting from compound 72 (1.67 g, 4.5 mmol). Amine 73 (1.06 g, 99%) was isolated as a white solid. 1H NMR (300 MHz, DMSO-d6) δ 1.32 (m, 2H), 1.54 (m, 2H) 2.55 (m, 2H), 3.45 (m, 2H), 3.75 (m, 3H), 3.94 (m, 2H), 6.83 (d, 2H), 7.08 (d, 2H).
Quellen und Nachweise
- ORD-Eintrag
- ord-174884ba832d461790c76f5063f95ecc
- Quelldatensatz
- uspto-grants-2007_03