HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethanol → Ethyl (2S,4EZ)-1-([1,1'-biphenyl]-4-ylcarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethanol | HCID 702 | — |
| Edukt | 4-Phenylbenzoyl chloride | HCID 84151 | — |
| Edukt | (2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid | HCID 58714586 | — |
| Produkt | Ethyl (2S,4EZ)-1-([1,1'-biphenyl]-4-ylcarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylate | HCID 131726289 | — |
Reaktionsschritte
Following the general method as outlined in Example 11, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, [1,1′-biphenyl]-4-carbonyl chloride, and ethanol, the title compound was isolated as a mixture of two isomers in 87.2% purity by HPLC.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07189754B2 |
| Quelldatensatz | uspto-grants-2007_03 |
| ORD ID | ord-cc96641ab87c4650bd6f8b607819d0a2 |
| Quellennotiz | uspto-grants-2007_03 |