Methanol → Methyl (2S,4EZ)-1-[(2'-cyano[1,1'-biphenyl]-4-yl)carbonyl]-4-(methoxyimino)-2-pyrrolidinecarboxylate

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Methanol	HCID 887	—
Edukt	4-(2-cyanophenyl)benzoic Acid	HCID 10727789	—
Edukt	(2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid	HCID 58714586	—
Produkt	Methyl (2S,4EZ)-1-[(2'-cyano[1,1'-biphenyl]-4-yl)carbonyl]-4-(methoxyimino)-2-pyrrolidinecarboxylate	HCID 131726291	—

Reaktionsschritte

Following the general method as outlined in Example 11, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, 2′-cyano[1,1′-biphenyl]-4-carboxylic acid, and methanol, the title compound was isolated as a mixture of two isomers in 91.6% purity by HPLC.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07189754B2
Quelldatensatz	uspto-grants-2007_03
ORD ID	ord-b371f7490fb64ff496c2c69ebcc534c5
Quellennotiz	uspto-grants-2007_03