HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4,6-Dichloropyrido[3,4-d]pyrimidine → (6-Chloropyrido[3,4-d]pyrimidin-4-yl)-(4-(3-fluorobenzyloxy)-phenyl)-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4,6-Dichloropyrido[3,4-d]pyrimidine | HCID 10821876 | — |
| Edukt | 4-(3-Fluoro-benzyloxy)-phenylamine | HCID 16775314 | — |
| Lösungsmittel | Acetonitrile | HCID 6342 | — |
| Produkt | (6-Chloropyrido[3,4-d]pyrimidin-4-yl)-(4-(3-fluorobenzyloxy)-phenyl)-amine | HCID 21952062 | — |
Reaktionsschritte
4,6-Dichloro-pyrido[3,4-d]pyrimidine (1 g) and 4-(3-fluorobenzyloxy)aniline (1.08 g) in acetonitrile (70 ml) were reacted together as in Procedure A. The product was collected by filtration as a yellow solid (1.86 g); m/z 381 (M+1)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07189734B2 |
| Quelldatensatz | uspto-grants-2007_03 |
| ORD ID | ord-61dcf84dd633487097b1eca0515955f7 |
| Quellennotiz | uspto-grants-2007_03 |