Reaktionsgleichung
C([O:3][C:4](=[O:21])[CH:5]([O:19][CH3:20])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]#[C:14][CH2:15][CH2:16][CH2:17]Br)=[CH:9][CH:8]=1)C.[F:22][C:23]1[CH:37]=[CH:36][CH:35]=[CH:34][C:24]=1[C:25]([C:27]1[CH:32]=[CH:31][C:30]([OH:33])=[CH:29][CH:28]=1)=[O:26]>>[F:22][C:23]1[CH:37]=[CH:36][CH:35]=[CH:34][C:24]=1[C:25]([C:27]1[CH:32]=[CH:31][C:30]([O:33][CH2:17][CH2:16][CH2:15][C:14]#[C:13][C:10]2[CH:9]=[CH:8][C:7]([CH2:6][C@H:5]([O:19][CH3:20])[C:4]([OH:3])=[O:21])=[CH:12][CH:11]=2)=[CH:29][CH:28]=1)=[O:26]Komponenten
3
Versuchsvorschrift
The title compound was prepared from 3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 24, Step A and 2-fluoro-4′-hydroxybenzophenone in a manner analogous to that described for Example 24, Step B. MS(ES) for C28H25FO5[M+H]+:461.2.
Quellen und Nachweise
- ORD-Eintrag
- ord-e5cfa7a924614a2f9ad0d39616fefe32
- Quelldatensatz
- uspto-grants-2007_03
- Patentnummer
- US07192982B2
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