HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
7-Hydroxyflavone → (2S)-2-Methoxy-3-{4-[3-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-propoxy]-phenyl}-propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 7-Hydroxyflavone | HCID 5281894 | — |
| Edukt | (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid | HCID 69424952 | — |
| Produkt | (2S)-2-Methoxy-3-{4-[3-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-propoxy]-phenyl}-propionic acid | HCID 58822836 | — |
Reaktionsschritte
The title compound was prepared from (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid linked to Wang's Resin (Example 94, Step D) via Mitsunobu coupling with 7-hydroxyflavone and cleavage from the resin (Standard Procedure G) gave an oily solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07192982B2 |
| Quelldatensatz | uspto-grants-2007_03 |
| ORD ID | ord-7a4feb1f8f80404081c313555e183b4e |
| Quellennotiz | uspto-grants-2007_03 |