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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 459256Erstellt: 25. Oktober 2026

Sodium Hydroxide → (2S)-2-Methoxy-3-(4-{3-[4-(3-phenyl-propionyl)-phenoxy]-propoxy}-phenyl)-propionic acid

https://huagongshe.com/reaction/459256

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktSodium HydroxideHCID 14798—
Edukt1-(4-Hydroxyphenyl)-3-phenylpropan-1-oneHCID 14416163—
Edukt(2S)-3-[4-(3-Bromopropoxy)-phenyl]-2-methoxy-propionic acid ethyl esterHCID 58822859—
Produkt(2S)-2-Methoxy-3-(4-{3-[4-(3-phenyl-propionyl)-phenoxy]-propoxy}-phenyl)-propionic acidHCID 10204975—

Reaktionsschritte

(2S)-3-[4-(3-Bromo-propoxy)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 173, Step A was treated with 1-(4-Hydroxy-phenyl)-3-phenyl-propan-1-one from Step A under the Standard Procedure J. The compound thus obtained was allowed to react under Standard hydrolysis procedure C (NaOH) to give the title compound. MS(ES) for C28H30O6 [M+NH4]+: 485 [M+H]+: 463.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07192982B2
Quelldatensatzuspto-grants-2007_03
ORD IDord-c7bb5812cc4748d6a8e2dd908bf45f85
Quellennotizuspto-grants-2007_03