5-Aminobenzimidazole → N-(4-Methoxybenzyl)-3H-benzo[d]imidazol-5-amine

Beteiligte Stoffe

Reaktionsschritte

Alternatively the compound was synthesized starting from benzimidazol-5-amine (2.66 g; 20 mmol; 1 eq.), 4-methoxybenzaldehyde (3.26 g; 2.9 ml; 24 mmol; 1.2 eq.), NaBH4 (1.14 g; 30 mmol; 1.5 eq.) and 5 N NaOH (20 ml; 100 mmol; 5 eq.) according to method 2; Yield: 4.53 g (89.5%); MS m/z: 254.3 [M+H]+

Herkunft & Nachweise