HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Chlorobenzaldehyde → N-(4-Chlorobenzyl)-3H-benzo[d]imidazol-5-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Chlorobenzaldehyde | HCID 7726 | — |
| Edukt | 5-Aminobenzimidazole | HCID 13623 | — |
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Sodium borohydride | HCID 4311764 | — |
| Produkt | N-(4-Chlorobenzyl)-3H-benzo[d]imidazol-5-amine | HCID 67444221 | — |
Reaktionsschritte
Alternatively the compound was synthesized starting from benzimidazol-5-amine (2.66 g; 20 mmol; 1 eq.), 4-chlorobenzaldehyde (3.09 g; 22 mmol; 1.1 eq.), NaBH4 (1.14 g; 30 mmol; 1.5 eq.) and 5 N NaOH (20 ml; 100 mmol; 5 eq.) according to method 2; Yield: 3.94 g (76.7%); MS m/z: 258.3/260.3 [M+H]+
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08541596B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-cefdeab8e05a489a85e32512c71a144a |
| Quellennotiz | uspto-grants-2013_09 |