HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(1,1'-Biphenyl)-2-ol → (2S)-3-{4-[2-(biphenyl-2-yloxy)-ethoxy]-phenyl}-2-methoxy-propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (1,1'-Biphenyl)-2-ol | HCID 7017 | — |
| Edukt | (2S)-3-[4-(2-bromo-ethoxy)-phenyl]2-methoxy-propionic acid ethyl ester | HCID 58822865 | — |
| Edukt | (2S)-2-methoxy-3-[4-(3-phenoxy propoxy)-phenyl]-propionic acid | HCID 58822897 | — |
| Produkt | (2S)-3-{4-[2-(biphenyl-2-yloxy)-ethoxy]-phenyl}-2-methoxy-propionic acid | HCID 58822810 | — |
Reaktionsschritte
The title compound was prepared from (2S)-3-[4-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (Example 283, Step 2) and biphenyl-2-ol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1), to produce a colorless oil. MS (ES) for C24H24O5 [M+Na]+: 415.4.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07192982B2 |
| Quelldatensatz | uspto-grants-2007_03 |
| ORD ID | ord-ab48810469af4ebcb430437bfe3081f8 |
| Quellennotiz | uspto-grants-2007_03 |