Tetrahydrofuran → HCID 22637025, Verbindung

Beteiligte Stoffe

Reaktionsschritte

To a THF solution of 4-bromo-2-chloroanisole was added an n-butyllithium/n-hexane solution at −78° C., followed by 30 minutes of stirring. Then, trimethyl borate was added and the whole was warmed to room temperature, followed by 30 minutes of stirring. Using the residue obtained by evaporation of the solvent instead of 3,4-dimethoxyphenylboric acid, an objective compound was obtained in a similar manner to Reference Example 1.

Herkunft & Nachweise