HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2H-Azepine, 3,4,5,6-tetrahydro-7-methoxy- → N-[(1R,2R)-2-cyclohexylcyclopentyl]piperidin-2-imine;hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2H-Azepine, 3,4,5,6-tetrahydro-7-methoxy- | HCID 75657 | — |
| Edukt | o-Methylvalerolactim | HCID 138567 | — |
| Edukt | cis-2-Cyclohexylcyclopentylamine hydrochloride | HCID 70050481 | — |
| Edukt | rac-(1R,2R)-2-phenylcyclopentan-1-amine hydrochloride | HCID 70051154 | — |
| Produkt | N-[(1R,2R)-2-cyclohexylcyclopentyl]piperidin-2-imine;hydrochloride | HCID 145795656 | — |
Reaktionsschritte
Following the procedure of Example 23, only substituting for cis-2-phenylcyclopentylamine hydrochloride and O-methylcaprolactim, appropriate amounts of cis-2-(cyclohexyl)cyclopentylamine hydrochloride and O-methylvalerolactim respectively the desired product is obtained, M.P. 195.5°-197° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04061746 |
| Quelldatensatz | uspto-grants-1977_12 |
| ORD ID | ord-f7e359947188445885dbe2d74e1dd436 |
| Quellennotiz | uspto-grants-1977_12 |