Bromo-4'-chloro-3'-sulfamoylacetophenone → 4-(4-Chloro-3-sulfamoylphenyl)-2-isobutylimino-3-methyl-1,3-thiazolidine-4-ol-hydrobromide
Reaktionsgleichung
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:11])[CH2:9][Br:10])=[CH:4][C:3]=1[S:12](=[O:15])(=[O:14])[NH2:13].[CH2:16]([NH:20][C:21]([NH:23][CH3:24])=[S:22])[CH:17]([CH3:19])[CH3:18]>>[BrH:10].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([OH:11])[CH2:9][S:22][C:21](=[N:20][CH2:16][CH:17]([CH3:19])[CH3:18])[N:23]2[CH3:24])=[CH:4][C:3]=1[S:12](=[O:15])(=[O:14])[NH2:13]Komponenten
3
Versuchsvorschrift
6.2 g of 4'-chloro-3'-sulfamoyl-2-bromoacetophenone and 3.0 g of 1-isobutyl-3-methylthiourea were reacted according to the prescription made in Example 23 and the colorless end product was precipitated with 200 ml of diethyl ether.
Aufarbeitung
- customthe colorless end product was precipitated with 200 ml of diethyl ether