HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetic Acid → Orotic Acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetic Acid | HCID 176 | — |
| Edukt | Urea | HCID 1176 | — |
| Edukt | Trichloroacetyl chloride | HCID 6420 | — |
| Edukt | 4,4,4-Trichloro-3-oxobutanoyl chloride | HCID 21391724 | — |
| Produkt | Orotic Acid | HCID 967 | — |
Reaktionsschritte
To recap, this invention involves: converting trichloroacetyl chloride with ketone to γ,γ ,γ -trichloroacetoacetyl chloride, adding the reaction mixture to urea dissolved in a polar organic solvent, e.g., acetic acid; evaporating out the resulting 6-trichloromethyluracil; and hydrolyzing the 6-trichloromethyluracil to form orotic acid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04064126 |
| Quelldatensatz | uspto-grants-1977_12 |
| ORD ID | ord-3be252f833cc47e5a14f6bf37e6b0113 |
| Quellennotiz | uspto-grants-1977_12 |