Cyclohexyl isothiocyanate → 2-(Cyclohexylaminothioxomethyl)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-hydrazine carboxamide

HRID 4618

Reaktionsgleichung

Reaktionsgleichung von HRID 4618
[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:20]=[CH:21][CH:22]=2)[O:11][CH2:12][CH2:13][CH2:14][NH:15][C:16]([NH:18][NH2:19])=[O:17])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:23]1([N:29]=[C:30]=[S:31])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1>>[CH:23]1([NH:29][C:30](=[S:31])[NH:19][NH:18][C:16]([NH:15][CH2:14][CH2:13][CH2:12][O:11][C:10]2[CH:20]=[CH:21][CH:22]=[C:8]([CH2:7][N:1]3[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)[CH:9]=2)=[O:17])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1

Komponenten

3

Edukt 2

HCID 14289Cyclohexyl isothiocyanateHCID 13657330N-(3-{3-[(Piperidin-1-yl)methyl]phenoxy}propyl)hydrazinecarboxamide

Produkt 1

HCID 136573462-(Cyclohexylaminothioxomethyl)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-hydrazine carboxamide

Versuchsvorschrift

The compound is prepared by a method analogous to that of Example 17 from N-[3-[3-(1-piperidinylmethyl) phenoxy]propyl]-hydrazine carboxamide and cyclohexyl isothiocyanate. The analytical values are summarized in Table I.

Quellen und Nachweise

ORD-Eintrag
ord-db19988b81484840bd818ac30406bb9b
Quelldatensatz
uspto-grants-1988_02
Patentnummer
US04727081

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