Ethanethiol → 2-chloroethanethiophosphonic acid S-ethyl ester N-monoisopropylamide

HRID 462011Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 462011
[CH2:1]([SH:3])[CH3:2].C(N(CC)CC)C.[Cl-].[CH:12]([NH:15][P:16]([CH2:19][CH2:20][Cl:21])(=[O:18])[OH:17])([CH3:14])[CH3:13]>C1C=CC=CC=1>[CH:12]([NH-:15])([CH3:14])[CH3:13].[CH2:1]([S:3][P:16]([CH2:19][CH2:20][Cl:21])(=[O:17])[OH:18])[CH3:2]

Komponenten

5

Edukt 3

HCID 6343EthanethiolHCID 8471TriethylamineHCID 867353082-chloroethanephosphonic acid N-monoisopropylamide chloride

Produkt 1

HCID 867353102-chloroethanethiophosphonic acid S-ethyl ester N-monoisopropylamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

13 g (0.2 mole) ethylmercaptan and 20 g (0.2 mole) triethylamine are added to 41 g (0.2 mole) 2-chloroethanephosphonic acid N-monoisopropylamide chloride in 100 ml benzene. Stirring was afterwards effected for 2 hours at 40° C; the salts were then filtered off with suction, the reaction solution was washed with water, and drying with sodium sulfate was carried out. After the solvent had been drawn off, there remained behind a crystalline residue, m.p. 51° C, yield: 15 g (33%) 2-chloroethanethiophosphonic acid S-ethyl ester N-monoisopropylamide.

Aufarbeitung

  1. filtrationthe salts were then filtered off with suction
  2. washthe reaction solution was washed with water
  3. dry with materialdrying with sodium sulfate

Quellen und Nachweise

ORD-Eintrag
ord-f7e0b7a378554beaa6617603c1906cbe
Quelldatensatz
uspto-grants-1977_12
Patentnummer
US04065288

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