HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Piperidine → 2-[2-(4-Methyl-1-piperazinyl)-5-thiadiazolyl)-1-methyl-5-nitroimidazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Piperidine | HCID 8082 | — |
| Edukt | 1-Methylpiperazine | HCID 53167 | — |
| Edukt | 2-(2-Piperidino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390837 | — |
| Produkt | 2-[2-(4-Methyl-1-piperazinyl)-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390838 | — |
Reaktionsschritte
The preparation of the above compound is carried out in the manner described for the 2-piperidino derivative (Example 28), an equivalent of 1-methylpiperazine replacing the piperidine. The crude product is purified by recrystallization from 2-methoxyethanol and melts at 242°-244° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04065567 |
| Quelldatensatz | uspto-grants-1977_12 |
| ORD ID | ord-174ca826ea4c410fb8561635a96caa59 |
| Quellennotiz | uspto-grants-1977_12 |