Ammonia → 4-Cyclopropyl-6-methoxy-1,3,5-triazin-2-amine

HRID 462342Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 462342
[NH3:1].[CH:2]1([C:5]2[N:10]=[C:9]([O:11][CH3:12])[N:8]=[C:7](C(Cl)(Cl)Cl)[N:6]=2)[CH2:4][CH2:3]1>O1CCCC1>[NH2:1][C:7]1[N:6]=[C:5]([CH:2]2[CH2:4][CH2:3]2)[N:10]=[C:9]([O:11][CH3:12])[N:8]=1

Komponenten

4

Edukt 2

HCID 222AmmoniaHCID 201996182-Cyclopropyl-4-methoxy-6-(trichloromethyl)-1,3,5-triazine

Produkt 1

HCID 27265914-Cyclopropyl-6-methoxy-1,3,5-triazin-2-amine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

5 ml of concentrated aqueous ammonia are added to a solution of 1 g of 2-cyclopropyl-4-methoxy-6-trichloromethyl-1,3,5-triazine in 3 ml of tetrahydrofuran; the whole is placed into a bomb tube and heated at 80° C. for 30 minutes. The mixture is cooled and then filtered; the filter residue is dissolved in 30 ml of methylene chloride, and the solution is dried over magnesium sulfate, and concentrated by evaporation. The residue crystallises to leave 0.4 g of white crystals, m.p. 157°-158° C.

Aufarbeitung

  1. customthe whole is placed into a bomb tube
  2. temperatureThe mixture is cooled
  3. filtrationfiltered
  4. dissolutionthe filter residue is dissolved in 30 ml of methylene chloride
  5. dry with materialthe solution is dried over magnesium sulfate
  6. concentrationconcentrated by evaporation
  7. customThe residue crystallises

Quellen und Nachweise

ORD-Eintrag
ord-593c4552262441719c11efb0f2912c02
Quelldatensatz
uspto-grants-1985_05
Patentnummer
US04515626

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