Pyrrolidine → 2-(Dimethoxymethyl)-6-hydroxy-2,5,7,8-tetramethyl-chroman-4-one

HRID 462581

Reaktionsgleichung

Reaktionsgleichung von HRID 462581
[C:1]([C:4]1[C:9]([OH:10])=[C:8]([CH3:11])[C:7]([CH3:12])=[C:6]([OH:13])[C:5]=1[CH3:14])(=[O:3])[CH3:2].[CH3:15][O:16][CH:17]([O:21][CH3:22])[C:18](=O)[CH3:19].N1CCCC1>C1(C)C=CC=CC=1>[CH3:15][O:16][CH:17]([O:21][CH3:22])[C:18]1([CH3:19])[CH2:2][C:1](=[O:3])[C:4]2[C:9](=[C:8]([CH3:11])[C:7]([CH3:12])=[C:6]([OH:13])[C:5]=2[CH3:14])[O:10]1

Komponenten

5

Edukt 3

HCID 31268PyrrolidineHCID 80650Pyruvic aldehyde dimethyl acetalHCID 10867205Ethanone, 1-(2,5-dihydroxy-3,4,6-trimethylphenyl)-

Produkt 1

HCID 130515362-(Dimethoxymethyl)-6-hydroxy-2,5,7,8-tetramethyl-chroman-4-oneAusbeute 70 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

15.0 g (77 mmoles) of acetyl-trimethylhydroquinone, 10.5 g (89 mmoles) of 1,1-dimethoxy-propan-2-one and 9.30 g (131 mmoles) of pyrrolidine were reacted in toluene solution by a method similar to that of Example 1 to give the above product. Boiling point: 165°-170° C./6.10-5 mbar (bulb tube); yield: 70%.

Aufarbeitung

  1. customto give the above product

Quellen und Nachweise

ORD-Eintrag
ord-3acfebb68dd044ffb37b002faf72c46d
Quelldatensatz
uspto-grants-1985_05
Patentnummer
US04515975

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