2-Naphthol → N-benzyloxycarbonyl glycine beta-naphthyl ester
Reaktionsgleichung
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[OH:11].[NH:12]([C:17]([O:19][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:18])[CH2:13][C:14](O)=[O:15]>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[O:11][C:14](=[O:15])[CH2:13][NH:12][C:17]([O:19][CH2:20][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)=[O:18]Komponenten
3
Versuchsvorschrift
β-Naphthol and Z-Gly.OH were treated in the same manner as in Example 78 to obtain N-benzyloxycarbonyl glycine β-naphthyl ester (hereinafter represented by ##STR10## in a yield of 72%.
Aufarbeitung
- additionOH were treated in the same manner as in Example 78
Quellen und Nachweise
- ORD-Eintrag
- ord-ed09abf9ebd94142bc248139abb05618
- Quelldatensatz
- uspto-grants-1979_11