2,3-Dihydro-2,4-dimethyl-7-nitrobenzofuran → HCID 13575669, Verbindung

HRID 465021Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 465021
[CH3:1][CH:2]1[CH2:6][C:5]2[C:7]([CH3:14])=[CH:8][CH:9]=[C:10]([N+:11]([O-])=O)[C:4]=2[O:3]1.[H][H]>[Ni].O1CCCC1>[NH2:11][C:10]1[C:4]2[O:3][CH:2]([CH3:1])[CH2:6][C:5]=2[C:7]([CH3:14])=[CH:8][CH:9]=1

Komponenten

5

Edukt 2

HCID 135756682,3-Dihydro-2,4-dimethyl-7-nitrobenzofuranHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 13575669HCID 13575669, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 935NickelKatalysatorHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

A mixture of 24.3 g of 1C, 200 ml of tetrahydrofuran (THF) and 2 g of activated Raney nickel catalyst was treated with hydrogen (40 psig) in a Parr shaker three hours, then filtered. The solvent was evaporated from the filtrate to give 7-amino-2,3-dihydro-2,4-dimethylbenzofuran (1D), as an amber syrup.

Aufarbeitung

  1. filtrationfiltered
  2. customThe solvent was evaporated from the filtrate

Quellen und Nachweise

ORD-Eintrag
ord-d11b2d305be64229a697beedc72a21a3
Quelldatensatz
uspto-grants-1985_10
Patentnummer
US04550121

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