Hydrazine → 2-Hydrazino-3,3'-bipyridine

HRID 465131Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 465131
Br[C:2]1[C:7]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:6][CH:5]=[CH:4][N:3]=1.[NH2:14][NH2:15]>N1C=CC=CC=1>[NH:14]([C:2]1[C:7]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:6][CH:5]=[CH:4][N:3]=1)[NH2:15]

Komponenten

4

Edukt 2

HCID 9321HydrazineHCID 135337192-Bromo-3,3'-bipyridine

Produkt 1

HCID 135337152-Hydrazino-3,3'-bipyridine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

A mixture of 16.46 g of 2'-bromo-3,3'-bipyridine, 24 ml of anhydrous hydrazine and 500 ml of dry pyridine was heated at 100° C. for 3 days. The solvent was removed under vacuum, toluene was added and removed and the residue was partitioned between saturated aqueous sodium carbonate and methylene chloride. The organic layer was dried, the solvent removed under vacuum and the residue crystallized from methylene chloride-hexane, giving 2'-hydrazino-3,3'-bipyridine as tan crystals.

Aufarbeitung

  1. customThe solvent was removed under vacuum, toluene
  2. additionwas added
  3. customremoved
  4. customthe residue was partitioned between saturated aqueous sodium carbonate and methylene chloride
  5. customThe organic layer was dried
  6. customthe solvent removed under vacuum
  7. customthe residue crystallized from methylene chloride-hexane

Quellen und Nachweise

ORD-Eintrag
ord-be94748dd56543058014dafbf39d5368
Quelldatensatz
uspto-grants-1985_10
Patentnummer
US04550166

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