L-Alanine → N-(3-Mercaptopropanoyl)-N-methyl-L-leucine

HRID 46539

Reaktionsgleichung

CN[C@H](C(O)=O)CC(C)C.N[C@H](C(O)=O)C.C([S:25][CH2:26][CH2:27][C:28]([N:30]([CH3:39])[C@H:31]([C:36]([OH:38])=[O:37])[CH2:32][CH:33]([CH3:35])[CH3:34])=[O:29])(=O)C1C=CC=CC=1.N[C@H](C(O)=O)CC(C)C>>[SH:25][CH2:26][CH2:27][C:28]([N:30]([CH3:39])[C@H:31]([C:36]([OH:38])=[O:37])[CH2:32][CH:33]([CH3:35])[CH3:34])=[O:29]

Komponenten

Edukt 4

HCID 5950L-Alanine

HCID 6106L-Leucine

HCID 2777993N-Methylleucine

HCID 86735141N-(3-benzoylthiopropanoyl)-N-methyl-L-leucine

Produkt 1

HCID 53978361N-(3-Mercaptopropanoyl)-N-methyl-L-leucine

Versuchsvorschrift

By substituting N-methyl-L-leucine for the L-alanine in the procedure of Example 1, and then treating the product by the procedure of Example 2, N-(3-benzoylthiopropanoyl)-N-methyl-L-leucine, and N-(3-mercaptopropanoyl)-N-methyl)-L-leucine are obtained.

Aufarbeitung

customare obtained

Quellen und Nachweise

ORD-Eintrag: ord-2d77b27380a64c0eac7c4d81e8d5f37f
Quelldatensatz: uspto-grants-1979_11
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US04173704

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