Diethyl Malonate → Diethyl 2-pent-4-enylpropanedioate

HRID 465543

Reaktionsgleichung

Reaktionsgleichung von HRID 465543
[Na].[C:2]([O:10][CH2:11][CH3:12])(=[O:9])[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5].Br[CH2:14][CH2:15][CH2:16][CH:17]=[CH2:18]>C(O)C>[CH2:18]([CH:3]([C:4]([O:6][CH2:7][CH3:8])=[O:5])[C:2]([O:10][CH2:11][CH3:12])=[O:9])[CH2:17][CH2:16][CH:15]=[CH2:14]

Komponenten

5

Edukt 3

HCID 7761Diethyl MalonateHCID 707041-Pentene, 5-bromo-HCID 5360545Sodium

Produkt 1

HCID 361718Diethyl 2-pent-4-enylpropanedioate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

To 300 ml of ethanol are added 5 g of sodium spheres and after a clear solution is obtained, 32.1 g of diethyl malonate is added in one portion. After 1 h at room temperature, 15 g of 5-bromopent-1-ene is added and the reaction mixture is stirred at room temperature for 16 h. The reaction mixture is evaporated to dryness and the residue is distilled under high vacuum to obtain diethyl pent-4-enylmalonate.

Aufarbeitung

  1. customafter a clear solution is obtained
  2. customThe reaction mixture is evaporated to dryness
  3. distillationthe residue is distilled under high vacuum

Quellen und Nachweise

ORD-Eintrag
ord-eab5d11f5c06433ca30c1f73b2b051f1
Quelldatensatz
uspto-grants-1992_10
Patentnummer
US05153214

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