Benzoyl chloride → HCID 14049623, Verbindung

HRID 466134Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 466134
C[Si](C)(C)[O:3][C:4]1[CH:9]=[C:8]([O:10][Si](C)(C)C)[CH:7]=[CH:6][N:5]=1.[C:17](Cl)(=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>ClCCl>[C:17]([O:3][C:4]1[CH:9]=[C:8]([O:10][C:17](=[O:24])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:7]=[CH:6][N:5]=1)(=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Komponenten

4

Edukt 2

HCID 7412Benzoyl chlorideHCID 21819823HCID 21819823, Verbindung

Produkt 1

HCID 14049623HCID 14049623, VerbindungAusbeute 24,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To 4.0 g of 2,4-bis(trimethylsilyloxy)-pyridine in 50 ml of dichloromethane were added 2.65 g of benzoyl chloride and 0.2 ml of stannic chloride, and the mixture was stirred at room temperature for one hour. The solvent was distilled off and the residue was subjected to silica gel chromatography using ethyl acetate-benzene (2:3) as an eluent to produce 0.74 g of the title compound in a yield of 14.8%.

Aufarbeitung

  1. distillationThe solvent was distilled off

Quellen und Nachweise

ORD-Eintrag
ord-19ced059d5cf4a31866ca35ad1ec7956
Quelldatensatz
uspto-grants-1992_10
Patentnummer
US05155113

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