HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → Alendronic Acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Tetramethyl phthalimido-1-hydroxybutylidene-bisphosphonate | HCID 9845824 | — |
| Produkt | Alendronic Acid | HCID 2088 | — |
Reaktionsschritte
contacting tetramethyl phthalimido-1-hydroxybutylidene-bisphosphonate from Step (b) with aqueous hydrochloric acid at a temperature in the range of 80° C. to reflux to form 4-amino-1-hydroxybutylidene-bisphosphonic acid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05159108 |
| Quelldatensatz | uspto-grants-1992_10 |
| ORD ID | ord-79a5b90cb2d34472b21ab1259fb3015e |
| Quellennotiz | uspto-grants-1992_10 |