Potassium Carbonate → HCID 12411034, Verbindung

HRID 46775

Reaktionsgleichung

Reaktionsgleichung von HRID 46775
[CH2:1]([NH:9][CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([O:20][CH3:21])[CH:13]=1)[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:28](I)[CH2:29][CH3:30]>CC(C)=O>[CH2:1]([N:9]([CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([O:20][CH3:21])[CH:13]=1)[CH2:28][CH2:29][CH3:30])[CH2:2][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Komponenten

5

Edukt 3

HCID 11430Potassium CarbonateHCID 336431-IodopropaneHCID 215356AN-465/43411221

Produkt 1

HCID 12411034HCID 12411034, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

A solution of 8 g of N-phenethyl-3,4-dimethoxyphenethylamine, 8 g of anhydrous potassium carbonate, 11 ml of propyl iodide and 80 ml of acetone was refluxed for 6 hours and the mixture was filtered. The filtrate was evaporated to dryness and the residue was taken up in 50 ml of water. The solution was extracted with methylene chloride and the organic extracts were washed with water, dried over magnesium sulfate, filtered and evaporated to dryness to obtain 9.37 g of raw N-phenethyl-N-propyl-3,4-dimethoxyphenethylamine in the form of an oil which was used as is for the next step.

Aufarbeitung

  1. filtrationthe mixture was filtered
  2. customThe filtrate was evaporated to dryness
  3. extractionThe solution was extracted with methylene chloride
  4. washthe organic extracts were washed with water
  5. dry with materialdried over magnesium sulfate
  6. filtrationfiltered
  7. customevaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-35c268dcc23843a9bd9cbd95b479e615
Quelldatensatz
uspto-grants-1979_11
Patentnummer
US04175136

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