3-Pyrroline → HCID 178501987, Verbindung

HRID 46825

Reaktionsgleichung

Reaktionsgleichung von HRID 46825
Cl[C:2]1[N:7]=[C:6]([NH:8][C:9]([O:11][CH3:12])=[O:10])[N+:5]([O-:13])=[C:4]([NH:14][C:15]([O:17][CH3:18])=[O:16])[CH:3]=1.[NH:19]1[CH2:23][CH:22]=[CH:21][CH2:20]1>C(Cl)Cl>[N:19]1([C:2]2[N:7]=[C:6]([NH:8][C:9]([O:11][CH3:12])=[O:10])[N+:5]([O-:13])=[C:4]([NH:14][C:15]([O:17][CH3:18])=[O:16])[CH:3]=2)[CH2:23][CH:22]=[CH:21][CH2:20]1

Komponenten

4

Edukt 2

HCID 660593-PyrrolineHCID 178501976HCID 178501976, Verbindung

Produkt 1

HCID 178501987HCID 178501987, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

A suspension of 12.5 g. of dimethyl 6-chloro-2,4-pyrimidine-dicarbamate-3-oxide in 100 ml. of methylene chloride is treated with 15 g. of 3-pyrroline and the mixture is stirred at room temperature under an argon atmosphere for 26 hours. The white precipitate formed is filtered off and recrystallized from a mixture of methylene chloride and methanol, there being obtained pure dimethyl 6-(3-pyrrolin-1-yl)-2,4-pyrimidine-dicarbamate-3-oxide, having a melting point of 206° C. (decomposition).

Aufarbeitung

  1. additionA suspension of 12.5 g
  2. customThe white precipitate formed
  3. filtrationis filtered off
  4. customrecrystallized from a mixture of methylene chloride and methanol, there

Quellen und Nachweise

ORD-Eintrag
ord-c429aa86ebdd4802a3cc08ddf271cb4f
Quelldatensatz
uspto-grants-1979_11
Patentnummer
US04175190

Verknüpfte Notizen

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