Thionyl Chloride → 3-Cyano-5-fluoro-benzoic acid chloride
Reaktionsgleichung
[C:1]([C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([F:12])[CH:11]=1)[C:6](O)=[O:7])#[N:2].S(Cl)([Cl:15])=O>>[C:1]([C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([F:12])[CH:11]=1)[C:6]([Cl:15])=[O:7])#[N:2]Komponenten
3
Versuchsvorschrift
1.65 g (10.0 mmol) 3-cyano-5-fluorobenzoic acid were boiled for 2 h with 7.27 mL (100 mmol) thionyl chloride with stirring. The reaction mixture was evaporated to dryness i. vac. and coevaporated twice with toluene. The residue was reacted further as the crude product.
Aufarbeitung
- customThe reaction mixture was evaporated to dryness i
- customThe residue was reacted further as the crude product
Quellen und Nachweise
- ORD-Eintrag
- ord-283c3667309b4b41b7d6e7a741c75ffd
- Quelldatensatz
- uspto-grants-2014_01
- Patentnummer
- US08629137B2
Notizen zur Reaktion
Wird geladen…