HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,8-Diazabicyclo(5.4.0)undec-7-ene → 1-Chloro-4-[(3-cyano-4-methoxybenzyl)amino]-6-phthalazine carbonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Edukt | 1,4-Dichlorophthalazine-6-carbonitrile | HCID 10656738 | — |
| Edukt | 5-(Aminomethyl)-2-methoxybenzonitrile | HCID 22744645 | — |
| Lösungsmittel | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Produkt | 1-Chloro-4-[(3-cyano-4-methoxybenzyl)amino]-6-phthalazine carbonitrile | HCID 86588311 | — |
Reaktionsschritte
1,4-Dichlorophthalazine-6-carbonitrile and 3-cyano-4-methoxybenzylamine were stirred at room temperature in 1-methyl-2-pyrrolidinone in the presence of DBU, whereby 1-chloro-4-[(3-cyano-4-methoxybenzyl)amino]-6-phthalazine carbonitrile was obtained as a less polar product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06699870B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-aad9c7dcdfaa41e987a456042a16bd74 |
| Quellennotiz | uspto-grants-2004_03 |