1-(4-Fluorophenyl)-2,2-dimethylcyclopropane-1-carboxylic acid → HCID 58349696, Verbindung
Reaktionsgleichung
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([C:13]([OH:15])=O)[CH2:10][C:9]2([CH3:12])[CH3:11])=[CH:4][CH:3]=1.[CH3:16][NH:17][C@H:18]1[CH2:37][N:22]2[C:23]3[C:28]([C:29]([CH2:30][C:31]([O:33]CCC)=[O:32])=[C:21]2[CH2:20][CH2:19]1)=[CH:27][CH:26]=[CH:25][CH:24]=3>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([C:13]([N:17]([CH3:16])[C@H:18]3[CH2:37][N:22]4[C:23]5[C:28]([C:29]([CH2:30][C:31]([OH:33])=[O:32])=[C:21]4[CH2:20][CH2:19]3)=[CH:27][CH:26]=[CH:25][CH:24]=5)=[O:15])[CH2:10][C:9]2([CH3:11])[CH3:12])=[CH:6][CH:7]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared using analogous procedures described in Example 1 (Method B) 1-(4-fluorophenyl)-2,2-dimethylcyclopropanecarboxylic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 449.
Quellen und Nachweise
- ORD-Eintrag
- ord-104d64e856c046cb9409d0fd7f9b90bf
- Quelldatensatz
- uspto-grants-2014_01