Methyl iodide → HCID 14405656, Verbindung

HRID 476628Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 476628
[I:1][CH3:2].[N:3]1[CH:8]=[CH:7][C:6]([C:9]([N:11]2[CH2:20][CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:12]2)=[O:10])=[CH:5][CH:4]=1>C(OCC)(=O)C>[I-:1].[CH3:2][N+:3]1[CH:4]=[CH:5][C:6]([C:9]([N:11]2[CH2:20][CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:12]2)=[O:10])=[CH:7][CH:8]=1

Komponenten

4

Edukt 2

HCID 6328Methyl iodideHCID 4137929HCID 4137929, Verbindung

Produkt 1

HCID 14405656HCID 14405656, VerbindungAusbeute 86,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

2 ml, equivalent to 4.26 g (30.2 mmol) of iodomethane and 6 g (25.2 mmol) of 2-[(4-pyridyl)carbonyl]1,2,3,4-tetrahydroisoquinoline are introduced into 200 ml of ethyl acetate, and the mixture is stirred for 24 h at room temperature. A yellow precipiatate forms, which is filtered off and washed with ether. 8.3 g of product are obtained, this being used without further treatment in the following stage.

Aufarbeitung

  1. filtrationA yellow precipiatate forms, which is filtered off
  2. washwashed with ether

Quellen und Nachweise

ORD-Eintrag
ord-15375fffbed04b289a3feccb6c476305
Quelldatensatz
uspto-grants-1989_12
Patentnummer
US04885302

Notizen zur Reaktion

Wird geladen…