1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → 1-Cyclopropyl-7-[2-(dimethylaminomethyl)morpholino]-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid	HCID 535414	—
Edukt	Dimethyl-morpholin-2-ylmethyl-amine	HCID 3401489	—
Produkt	1-Cyclopropyl-7-[2-(dimethylaminomethyl)morpholino]-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid	HCID 10454056	—

Reaktionsschritte

By the use of 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 2-(dimethylaminomethyl)morpholine, the reaction is similarly carried out as Example 1 to give 1-cyclopropyl-7-[2-(dimethylaminomethyl)morpholino]-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, melting at 182°-183° C.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US04889857
Quelldatensatz	uspto-grants-1989_12
ORD ID	ord-a59dfd2d09974ac0be9401af878d1de9
Quellennotiz	uspto-grants-1989_12