HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,2-Diiodoethane → 2-(4-Trifluoromethylphenyl)-5-iodothiazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,2-Diiodoethane | HCID 12224 | — |
| Edukt | 2-(4-(Trifluoromethyl)phenyl)thiazole | HCID 14601969 | — |
| Edukt | Butyllithium | HCID 178418339 | — |
| Lösungsmittel | Diethyl Ether | HCID 3283 | — |
| Lösungsmittel | Hexane | HCID 8058 | — |
| Produkt | 2-(4-Trifluoromethylphenyl)-5-iodothiazole | HCID 14601970 | 46,5% |
Reaktionsschritte
In a manner similar to Step C of Example 1, the reaction of 5.45 grams (0.0238 mole) of 2-(4-trifluoromethylphenyl)thiazole, 9.5 ml of a 2.5 M solution of n-butyllithium in hexane, and 6.71 grams (0.0238 mole) of 1,2-diiodoethane in 40 ml of diethyl ether produced 3.93 grams of 2-(4-trifluoromethylphenyl)-5-iodothiazole as a solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04889867 |
| Quelldatensatz | uspto-grants-1989_12 |
| ORD ID | ord-952bda2a830d45e2b3066c627e9e143c |
| Quellennotiz | uspto-grants-1989_12 |