3-(Methylthio)phenylacetic acid → N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

HRID 478817Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 478817
[CH3:1][S:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]([OH:12])=O)[CH:6]=[CH:7][CH:8]=1.[CH2:13]([O:17][C:18](=[O:22])[C@H:19]([CH3:21])[NH2:20])[CH:14]([CH3:16])[CH3:15]>>[CH2:13]([O:17][C:18](=[O:22])[C@H:19]([CH3:21])[NH:20][C:10](=[O:12])[CH2:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([S:2][CH3:1])[CH:4]=1)[CH:14]([CH3:16])[CH3:15]

Komponenten

3

Edukt 2

HCID 27374613-(Methylthio)phenylacetic acidHCID 137435562-methylpropyl (2S)-2-aminopropanoate

Produkt 1

HCID 15481777N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

Versuchsvorschrift

Following General Procedure I above, and using 3-methylthiophenylacetic acid (CAS# 18698-73-2) and alanine iso-butyl ester (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Aufarbeitung

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

Quellen und Nachweise

ORD-Eintrag
ord-d7376b08bb584b76bfc5fa3dada63890
Quelldatensatz
uspto-grants-2003_11
Patentnummer
US06642261B2

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