(R)-2-(Cyclohexylmethyl)succinic acid-1-methyl ester → HCID 178500550, Verbindung
Reaktionsgleichung
N1(C(C2CCCCC2C(O)=O)=O)CCOCC1.[Cl:18][C:19]1[CH:34]=[CH:33][C:22]2[NH:23][C:24]([C:26]3[CH:31]=[CH:30][C:29]([NH2:32])=[CH:28][CH:27]=3)=[N:25][C:21]=2[CH:20]=1.[CH3:35][O:36][C:37](=[O:50])[C@H:38]([CH2:43][CH:44]1[CH2:49][CH2:48][CH2:47][CH2:46][CH2:45]1)[CH2:39][C:40](O)=[O:41]>>[CH3:35][O:36][C:37](=[O:50])[CH:38]([CH2:43][CH:44]1[CH2:45][CH2:46][CH2:47][CH2:48][CH2:49]1)[CH2:39][C:40]([NH:32][C:29]1[CH:28]=[CH:27][C:26]([C:24]2[NH:23][C:22]3[CH:33]=[CH:34][C:19]([Cl:18])=[CH:20][C:21]=3[N:25]=2)=[CH:31][CH:30]=1)=[O:41]Komponenten
4
Versuchsvorschrift
This compound was prepared by the procedure described in Example 1 part (a) from 4-(5-Chloro-1H-benzoimidazol-2-yl)-phenylamine and (R)-2-(Cyclohexylmethyl) succinic acid 1-methyl ester to give the crude product (2.0 g, 51%), which was used in the next step without further purification.