Benzeneacetic acid, 2-fluoro- → 2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester

HRID 480895

Reaktionsgleichung

Reaktionsgleichung von HRID 480895
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=O.[NH2:12][CH:13]([CH2:21][CH3:22])[C:14]([O:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[O:15]>>[CH2:17]([O:16][C:14](=[O:15])[CH:13]([NH:12][C:9](=[O:11])[CH2:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[F:1])[CH2:21][CH3:22])[CH:18]([CH3:19])[CH3:20]

Komponenten

3

Edukt 2

HCID 67979Benzeneacetic acid, 2-fluoro-HCID 13743360Isobutyl 2-aminobutyrate

Produkt 1

HCID 536432492-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester

Versuchsvorschrift

Following General Procedure BI above and using 2-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Aufarbeitung

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

Quellen und Nachweise

ORD-Eintrag
ord-38733695a08a4aa69a7329b0114245bb
Quelldatensatz
uspto-grants-2003_11
Patentnummer
US06653303B1

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