Potassium Hydroxide → 4-(5,5,6,6,7,7,8,8,8-Nonafluoro-octyl)-cyclohex-3-enecarboxylic acid

HRID 48112Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 48112
C([O:3][C:4]([CH:6]1[CH2:11][CH2:10][C:9]([CH2:12][CH2:13][CH2:14][CH2:15][C:16]([F:28])([F:27])[C:17]([F:26])([F:25])[C:18]([F:24])([F:23])[C:19]([F:22])([F:21])[F:20])=[CH:8][CH2:7]1)=[O:5])C.[OH-].[K+]>O.C(O)C>[F:27][C:16]([F:28])([C:17]([F:25])([F:26])[C:18]([F:23])([F:24])[C:19]([F:22])([F:20])[F:21])[CH2:15][CH2:14][CH2:13][CH2:12][C:9]1[CH2:10][CH2:11][CH:6]([C:4]([OH:5])=[O:3])[CH2:7][CH:8]=1

Komponenten

4

Edukt 2

HCID 14797Potassium HydroxideHCID 867593684-(5,5,6,6,7,7,8,8,8-Nonafluoro-octyl)-cyclohex-3-enecarboxylic Acid Ethyl Ester

Produkt 1

HCID 206321594-(5,5,6,6,7,7,8,8,8-Nonafluoro-octyl)-cyclohex-3-enecarboxylic acidAusbeute 93 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 19096565Water ethanolLösungsmittel

Versuchsvorschrift

A solution 4-(5,5,6,6,7,7,8,8,8-nonafluoro-octyl)-cyclohex-3-enecarboxylic acid ethyl ester (41) (1 equi.) and potasium hydroxide (3.5 equi.) in water-ethanol (1:1) (25 mL/mmole) was stirred at 80 C temperature for 2 h., cooled to room temperature and quenched with hydrochloric acid (5%), filtered resulted white solid, washed with water and dried under vacuum to give 4-(5,5,6,6,7,7,8,8,8-nonafluoro-octyl)-cyclohex-3-enecarboxylic acid (42) as a white solid (93%).

Aufarbeitung

  1. customquenched with hydrochloric acid (5%)
  2. filtrationfiltered
  3. customresulted white solid
  4. washwashed with water
  5. customdried under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-a7b479eeafe747819e2c1e5af927d0a5
Quelldatensatz
uspto-grants-2004_03
Patentnummer
US06703082B1

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