2',3'-Difluoro-4'-(7,7,8,8,9,9,10,10,10-nonafluoro-decyloxy)-biphenyl-4-carboxylic Acid → 2',3'-Difluoro-4'-(7,7,8,8,9,9,10,10,10-nonafluoro-decyloxy)-biphenyl-4-carboxylic acid 4-[(R)-1-trifluoromethyl-heptyloxycarbonyl]-phenyl ester

HRID 48125Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 48125
[F:1][C:2]1[C:7]([F:8])=[C:6]([O:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]([F:28])([F:27])[C:17]([F:26])([F:25])[C:18]([F:24])([F:23])[C:19]([F:22])([F:21])[F:20])[CH:5]=[CH:4][C:3]=1[C:29]1[CH:34]=[CH:33][C:32]([C:35]([OH:37])=[O:36])=[CH:31][CH:30]=1.[F:38][C:39]([F:92])([F:91])[C@H:40]([O:47][C:48]([C:50]1[CH:55]=[CH:54][C:53](OC(C2C=CC(C3C=CC(OCCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)=C(F)C=3F)=CC=2)=O)=[CH:52][CH:51]=1)=[O:49])[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46]>>[F:38][C:39]([F:91])([F:92])[C@H:40]([O:47][C:48]([C:50]1[CH:51]=[CH:52][C:53]([O:36][C:35]([C:32]2[CH:33]=[CH:34][C:29]([C:3]3[CH:4]=[CH:5][C:6]([O:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]([F:27])([F:28])[C:17]([F:25])([F:26])[C:18]([F:23])([F:24])[C:19]([F:22])([F:20])[F:21])=[C:7]([F:8])[C:2]=3[F:1])=[CH:30][CH:31]=2)=[O:37])=[CH:54][CH:55]=1)=[O:49])[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46]

Komponenten

3

Edukt 2

HCID 206321522',3'-Difluoro-4'-(7,7,8,8,9,9,10,10,10-nonafluoro-decyloxy)-biphenyl-4-carboxylic AcidHCID 867593732',3'-difluoro-4'-(5,5,6,6,7,7,8,8,8-nonafluoro-octyloxy)-biphenyl-4-carboxylic acid 4-[(R)-1-trifluoromethyl-heptyloxycarbonyl]-phenyl ester

Produkt 1

HCID 867593742',3'-Difluoro-4'-(7,7,8,8,9,9,10,10,10-nonafluoro-decyloxy)-biphenyl-4-carboxylic acid 4-[(R)-1-trifluoromethyl-heptyloxycarbonyl]-phenyl ester

Versuchsvorschrift

2′,3′-Difluoro-4′-(7,7,8,8,9,9,10,10,10-nonafluoro-decyloxy)-biphenyl-4-carboxylic acid 4-[(R)-1-trifluoromethyl-heptyloxycarbonyl]-phenyl ester (15B) was prepared from 2′,3′-difluoro-4′-(7,7,8,8,9,9,10,10,10-nonafluoro-decyloxy)-biphenyl-4-carboxylic acid (14B) as described in the preparation 2′,3′-difluoro-4′-(5,5,6,6,7,7,8,8,8-nonafluoro-octyloxy)-biphenyl-4-carboxylic acid 4-[(R)-1-trifluoromethyl-heptyloxycarbonyl]-phenyl ester (15A) yielding 2′,3′-difluoro-4′-(7,7,8,8,9,9,10,10,10-nonafluoro-decyloxy)-biphenyl-4-carboxylic acid 4-[(R)-1-trifluoromethyl-heptyloxycarbonyl]-phenyl ester (15B)) as a white solid (88%).

Quellen und Nachweise

ORD-Eintrag
ord-f770866ce2e14e29a5926a487c803689
Quelldatensatz
uspto-grants-2004_03
Patentnummer
US06703082B1

Notizen zur Reaktion

Wird geladen…