Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 481303Erstellt: 25. Oktober 2026

Triethylamine → Methyl 4-[[4-[phenyl-(2-pyridyl)methyl]-1-piperazinyl]methyl]phenylacetate

https://huagongshe.com/reaction/481303

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktTriethylamineHCID 8471—
Edukt1-[Phenyl(pyridin-2-yl)methyl]piperazineHCID 3346446—
EduktMethyl 2-(4-(bromomethyl)phenyl)acetateHCID 11770640—
Lösungsmittel1,4-DioxaneHCID 31275—
ProduktMethyl 4-[[4-[phenyl-(2-pyridyl)methyl]-1-piperazinyl]methyl]phenylacetateHCID 1906614051,9%

Reaktionsschritte

Using 2.8 g of methyl 4-bromomethylphenylacetate, 2.9 g of 1-[phenyl-(2-pyridyl)methyl]piperazine, 2 ml of triethylamine, and 100 ml of dioxane, the reaction procedure of Example 1 was otherwise repeated and recrystallized from benzene-hexane to provide 2.47 g of methyl 4-[[4-[phenyl-(2-pyridyl)methyl]-1-piperazinyl]methyl]phenylacetate melting at 122° C.-123° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05789409
Quelldatensatzuspto-grants-1998_08
ORD IDord-f030a43e90ea46ddaeea19e7c57234b7
Quellennotizuspto-grants-1998_08